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[Medical ML] Failed Implementations: What Went Wrong

Posted on February 8, 2026February 10, 2026 by Yoman

Failed Implementations: What Went Wrong

Article #11 in Medical ML for Ukrainian Doctors Series

By Oleh Ivchenko | Researcher, ONPU | Stabilarity Hub | February 8, 2026


đź“‹ Key Questions Addressed

  1. What are the most significant high-profile failures of medical AI implementations?
  2. What technical, organizational, and deployment factors cause AI systems to fail?
  3. What lessons can Ukrainian healthcare learn to avoid repeating these failures?

Context: Why This Matters for Ukrainian Healthcare

Despite over $66.8 billion invested globally in healthcare AI (2021 alone), the field has produced spectacular failures alongside its successes. Understanding what went wrong—and why—is essential for any hospital considering AI adoption.


The High-Profile Failures: Case Studies

đź”´ IBM Watson Health: A $5 Billion Lesson

Perhaps no failure looms larger than IBM Watson Health—the company’s flagship attempt to revolutionize cancer care with AI.

Year Event
2011 Watson wins Jeopardy, IBM pivots to healthcare
2015-2016 Aggressive acquisitions totaling $5+ billion
Peak 7,000 employees dedicated to Watson Health
2018 Internal document reveals “unsafe and incorrect” recommendations
2022 IBM sells Watson Health for ~$1 billion ($4B write-off)

❌ What Went Wrong

  • Synthetic training data: Trained on hypothetical cases, not real patients
  • Poor real-world performance: 96% concordance at MSK → 12% for gastric cancer in China
  • Dangerous recommendations: Suggested chemotherapy for patients with severe infection
  • Limited adaptability: Couldn’t incorporate breakthrough treatments

đź”´ Google Health’s Thailand Diabetic Retinopathy Deployment

Google’s diabetic retinopathy AI claimed “>90% accuracy at human specialist level.” Field deployment told a different story.

📊 The Promise

  • Accuracy: >90% (specialist-level)
  • Processing time: <10 minutes per scan
  • Target: 4.5 million Thai patients

❌ The Reality

  • >21% of images rejected as unsuitable
  • Poor lighting in rural clinic environments
  • Only 10 patients screened in 2 hours

“Patients like the instant results, but the internet is slow and patients then complain. They’ve been waiting here since 6 a.m., and for the first two hours we could only screen 10 patients.”

— Thai clinic nurse (MIT Technology Review)

đź”´ Epic’s Sepsis Prediction Model

Epic’s sepsis prediction model represents a failure at scale—deployed across hundreds of US hospitals, affecting millions of patients.

Metric Epic’s Claim Actual Performance
AUC 0.76-0.83 0.63
Sensitivity Not disclosed 33%
False alarm ratio Not disclosed 109 alerts per 1 true intervention
⚠️ Impact: The model identified only 7% of patients who actually developed sepsis—a far cry from its marketed performance.

Algorithmic Bias: Systematic Discrimination at Scale

The Optum Algorithm: 200 Million Patients Affected

200M

Patients affected annually

$1,800

Less spent by Black patients (same illness)

2.7x

Improvement after correction

Root cause: Algorithm used healthcare spending as proxy for health need. Black patients spent less due to access barriers, not better health—creating systematic discrimination.

Skin Cancer Detection: Racial Performance Gaps

System Light Skin Dark Skin Drop
System A 0.41 0.12 -71%
System B 0.69 0.23 -67%
System C 0.71 0.31 -56%

Common Failure Patterns

“`mermaid
mindmap
root((AI Failure
Patterns))
Technical Failures
Shortcut learning
Training/deployment mismatch
Dataset shift
Organizational Failures
Ignoring clinician input
Underestimating integration
Missing baselines
Deployment Failures
Infrastructure gaps
Alert fatigue
Workflow disruption
Bias Failures
Demographic gaps in training
Proxy variable discrimination
Missing subgroup testing
“`

Shortcut Learning: When AI Learns the Wrong Features

COVID-19 Detection AI Learned to detect patient position (standing vs. lying) rather than lung pathology
Pneumonia AI Recognized hospital equipment/labels rather than disease patterns
Skin Cancer AI Used presence of rulers (dermatologists measure suspicious lesions) as cancer indicator

Key Lessons for Ukrainian Healthcare

âś… What To Do

  1. Validate locally: Never trust vendor performance claims without local testing
  2. Test on edge cases: Include diverse populations and challenging cases
  3. Measure baselines: Know current performance before deploying AI
  4. Plan for infrastructure: Consider internet, lighting, equipment quality
  5. Involve clinicians early: Design with end-users, not for them

❌ What To Avoid

  1. Synthetic training data: Hypothetical cases ≠ real patients
  2. Single-site validation: Performance varies across settings
  3. Ignoring alert fatigue: Too many alerts = all alerts ignored
  4. Proxy variable bias: Spending ≠ health need
  5. Overconfidence in lab metrics: AUC in lab ≠ AUC in clinic

Conclusions

🔑 Key Takeaways

  1. Failures are systemic, not anomalies: Even well-funded, prestigious projects fail when they ignore clinical reality
  2. Lab performance ≠ clinical performance: The gap between research and deployment is where most AI fails
  3. Bias is built-in, not accidental: Training data reflects historical inequities; active mitigation is required
  4. Infrastructure matters as much as algorithms: Network speed, image quality, workflow integration determine success
  5. Learning from failures is more valuable than celebrating successes

Questions Answered

âś… What are the most significant failures?

IBM Watson Health ($5B loss), Google’s Thailand deployment (21% image rejection), Epic’s sepsis model (missed 67% of cases), and Optum’s biased algorithm (200M patients affected).

âś… What factors cause failure?

Synthetic training data, infrastructure mismatches, algorithmic bias, alert fatigue, and underestimating deployment complexity.

âś… What lessons apply to Ukraine?

Always validate locally, involve clinicians from day one, plan for infrastructure requirements, and never trust vendor performance claims without independent testing.


Next in Series: Article #12 – Physician Resistance: Causes and Solutions

Series: Medical ML for Ukrainian Doctors | Stabilarity Hub Research Initiative


Author: Oleh Ivchenko | ONPU Researcher | Stabilarity Hub

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